DURHAM, N.C., Jan. 14, 2022 (GLOBE NEWSWIRE) — Novan, Inc. (“the Company” or “Novan”) (Nasdaq: NOVN), today announced that data from the Company’s completed Phase 2 and Phase 3 clinical studies of berdazimer 10.3% gel (previously referred to as SB206) for molluscum contagiosum will be presented at the 2022 Winter Clinical Dermatology Conference, being held January 14-19, 2022, in Koloa, Hawaii.
Berdazimer 10.3% gel, containing new chemical entity berdazimer (sodium), is in late-stage development and poised as a first-in-class topical controlled-nitric oxide releasing medication for the treatment of molluscum contagiosum, a highly contagious viral skin disease affecting an estimated 6 million people in the US, mostly children, if approved. There is currently no US Food & Drug Administration (FDA) approved medication indicated for the treatment of molluscum. If approved, the Company believes berdazimer 10.3% gel would offer those infected with molluscum a potential prescription therapeutic approach that could allow patients and/or caregivers to directly apply treatment gel to molluscum lesions.
The data presented at Winter Clinical features the efficacy and safety data from the Phase 2 study as well as Beginning of the End (BOTE) sign data collected from three Phase 3 studies. The latter represents a clinical sign of inflammation and imminent resolution of molluscum lesions that has never been prospectively studied in a molluscum clinical trial.
About the Poster Presentations:
Title: BOTE (Beginning Of The End) is a Clinical Sign of Molluscum Contagiosum Resolution Enhanced by SB206, an Investigational Nitric Oxide–Releasing Topical Medication
Authors: Tomoko Maeda-Chubachi, MD, PhD, MBA, Martina Cartwright, PhD, Elaine Siegfried, MD
Title: Results of Phase 2 Study Evaluating the Efficacy and Safety of SB206, Topical Berdazimer Sodium Gel, in Subjects with Molluscum Contagiosum
Authors: John Browning, MD, Adelaide Hebert, MD, Carolyn Enloe, MPH, Tomoko Maeda-Chubachi, MD, Martina Cartwright, PhD
Posters appear throughout the meeting within the Poster Gallery in the Grand Promenade of the Grand Hyatt Kauai.
For more information about the conference, visit: https://fallclinical.health/
About Novan
Novan, Inc. is a pre-commercial nitric oxide-based pharmaceutical company focused on dermatology and anti-infective therapies. We leverage our core synergies of science, capital, resources and patient needs to create value by bringing new nitric oxide-based medicines to market. Our goal is to create the world’s leader in nitric oxide-based science, technology, and clinical translation in support of delivering safe and efficacious therapies using our proprietary nitric oxide-based technology platform, NITRICIL
Forward-Looking Statements
Any statements contained in this press release that do not describe historical facts may constitute forward-looking statements as that term is defined in the Private Securities Litigation Reform Act of 1995. These statements may be identified by words such as “believe,” “expect,” “target,” “anticipate,” “may,” “plan,” “potential,” “will,” and similar expressions, and are based on the Company’s current beliefs and expectations. These forward-looking statements include, but are not limited to, statements related to the potential therapeutic value of the Company’s NITRICIL
INVESTOR AND MEDIA CONTACT:
Jenene Thomas
JTC Team, LLC
833-475-8247
NOVN@jtcir.com
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