Primary Hepatocytes Market to Surpass US$ 486 Million, Expanding at 6.6% CAGR by 2034 | Fact.MR Analysis

Rockville, MD, Feb. 05, 2025 (GLOBE NEWSWIRE) — In 2019, the net worth of the global primary hepatocytes market was around US$ 189.5 million. According to Fact.MR estimates this value is going to be around US$ 255.6 million in 2024. The global demand for primary liver cells, or hepatocytes, is expected to increase at a pace of 6.6% per year until 2034. By the end of 2034, the primary hepatocytes industry valuation is expected to reach up to US$ 486 million.

Ongoing undertakings and progress in the study of liver cell toxicity are the key reasons driving the sales of primary hepatocytes in the healthcare biotechnology sector. The growing emphasis on drug metabolism investigation has increased the demand for hepatocyte function studies in the pharmaceutical industries as well. The adoption of proper hepatocyte isolation methods has been heightened by regulatory authorities’ increased concern about safety evaluation in drug development as well as for species used. 

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Key Takeaways

• The primary hepatocytes industry in North America is estimated to be around US$ 88 million in 2024, which is 34.6% of the global market share.
• The United States accrues around 80% of the North American market and is poised to advance further with a 5.1% CAGR through 2034.
• While Canada is likely to witness a CAGR of 6.2%, Mexico is likely to experience a CAGR of 8.6% through the projected years.
• The total sales of the primary hepatocytes market in East Asia are expected to garner a revenue of around US$ 47 million in 2024.
• China is estimated to contribute 47.9% of the East Asia market in 2024 and is expected to progress at 6.5% CAGR through 2034.
• Till 2034, primary hepatocyte suppliers in Japan and South Korea are expected to experience 7.8% and 8.5% CAGRs, respectively, on average.

“The demand for primary hepatocytes is expected to rise further, fueled by the growth in in vitro toxicological testing cellular models that replicate liver function in humans. In addition to this, the need for primary hepatocytes is expected to be stimulated by global collaboration in liver regeneration research studies in the coming days.“ says a Fact.MR analyst.

Leading Players Driving Innovation in the Primary Hepatocytes Market:

Key players in the primary hepatocytes market include Thermo Fisher Scientific, Corning Inc., Lonza, Axol Bioscience Ltd., LifeNet Health, SEKISUI XenoTech, LLC, Cytes Biotechnologies, Cell Biologics, Inc., ZenBio, Inc., BioIVT, ScienCell Research Laboratories, Inc., Kerafast, Takara Bio Inc., and Kosheeka.

Competitive Landscape:

The overall market is highly concentrated as a few market players account for more than 60% of the global demand for primary liver cell lines. Also, there has been a sizable share of new primary hepatocyte market suppliers in recent years due to the drug discovery and development initiatives undertaken by contract research organizations.

Recent Developments by the Primary Hepatocyte Industry Participants:

• In September 2021, Sekisui XenoTech, LLC expanded its portfolio of proprietary CryostaX products to include hepatocyte cell lines from rodents and monkeys. However, these cells are only intended for use in several scientific applications, such as disease modeling, toxicity testing, and drug development for liver treatment.
• In October 2020, BioIVT Company released a new hepatocyte isolation kit, HEPATOMUNE. It is a long-term, stable in vitro model for investigating immune-related and inflammation-mediated liver damage.

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Primary Hepatocytes Industry News:

• In May 2022, the US-based BioIVT Company announced that its recently launched line of human primary hepatic cells now includes high-purity Kupffer cells. The company goes on to say that these new cells are meant to help with the development of various liver disease treatments and medications.
• HemaCare Corp., one of the leading providers of primary hepatocytes for use in clinical and research settings, was acquired by the US-based Charles River Laboratories in January 2022. Following this acquisition, Charles River intends to expand its scientific capabilities in the area of high-growth cell therapy.

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